Physicians have been using Platelet Rich Plasma (PRP) injection to aid the healing of bones after spinal injury and soft tissue recovery since the mid nineties. Although there is still no strong evidence, several scientific studies support the hypothesis that Platelet Rich Plasma (PRP) therapy really appears to speed healing and bone formation.
Platelet-Rich Plasma Have a Positive Effect on Bone Density Immediately Following Tooth Extraction
According to an article in the Journal of Oral Implantology, the use of PRP following tooth removal increases the rate of bone formation and decreases the healing time.
Bone loss is a common result after tooth extraction. Bone formation is a slow process, which normally takes about 16 weeks for the socket to heal completely after tooth removal. Poor healing can lead to excessive bone loss in the jaw that can delay tooth replacement. It can lead to expensive reconstructive surgery, or even be impossible to fix.
For the study, the research team followed patients who underwent wisdom tooth extraction. They have used radiography techniques with participants to detect bone changes after surgery. For each patient, researchers applied Platelet Rich Plasma (PRP) to one side of the mouth and left the other side untreated, serving as the control.
Researchers x-rayed the patients for evaluations and digital radiographs at various intervals in the 24-week follow-up period. The team checked them visually to evaluate the changes in their jaw bone density, inflammation, bleeding and pain.
Researchers have found a significant increase in bone density in the PRP-treated side of the mouth. Moreover, the Platelet Rich Plasma had a positive effect on bone density immediately following tooth extraction, and decreased the time necessary to return to full function.
What is particularly interesting is that it took approximately 6 weeks for control extraction sites to reach the same bone density that the PRP-treated sites achieved at first week.
Participants did not notice differences in their perception of bleeding, pain, or temperature between the different sites.
The Application of PRP in Bone Healing
Several scientific studies showed that the use of Platelet Rich Plasma (PRP) with bone graft could significantly improve the quality of bone healing in rabbits. One such study from Iranian researchers found that human Platelet Rich Plasma treatments have positive effect on bone healing in rabbits.
Radiographic evidence was taken on the first day and 2, 4, 6 and 8 weeks post surgery to evaluate bone formation, union and remodeling.
The results were promising. The team concluded that PRP promoted bone regeneration in the rabbit model. To read the full study, click here: (link)
The studies on the effect of PRP on bone healing were not all positive. Mixed results were reported and therefore no definitive conclusions could be drawn. In accordance, it is necessary to make a new study on human model in order to make a valid conclusion. However, the present findings are quite promising.
Joint Healing Center in NYC uses innovative techniques as Prolotherapy, Platelet Rich Plasma and Ultrasound guided Nerve Blocks to heal tendon or ligament tears associated with sports injuries and also heal arthritic degenerative joints. Our Physicians are Board Certified and very proficient in implementing this revolutionary techniques in the management of Arthritic or Traumatic Pain.